منابع مشابه
[Cancer stem cells in solid tumors].
In this review, we discuss recent issues about cancer stem cells, especially in solid tumors. Cancer stem cells show the ability to self-renew; and they possess multi-potential differentiation and tumorigenic potential. Cancer stem cells are reported to show resistance to anticancer drugs and radiotherapy, and therefore, they are involved in progression, recurrence, and metastasis in cancer. Th...
متن کاملCancer stem cells in solid tumors
Cancer stem cells (CSCs) are cells that drive tumorigenesis, as well as giving rise to a large population of differentiated progeny that make up the bulk of the tumor, but that lack tumorigenic potential. CSCs have been identified in a variety of human tumors, as assayed by their ability to initiate tumor growth in immunocompromised mice. Further characterization studies have demonstrated that ...
متن کاملTumor - Host Celi Hybrids in Radiochimeras ( in vivo hybrid / enzyme - deficient solid tumors / ascites tumors / macrophage )
F1 hybrid mice syngeneic or semiallogeneic with respect to the relevant tumor were lethally irradiated and then reconstituted with hemopoietic cells from strain CBAT6T6 mice. After chimerism had been established, the animals were inoculated with solid or ascites tumors. Tumor-host cell hybrids were selected from enzyme-deficient solid tumors by explanting the tumor cell suspension into hypoxant...
متن کاملCancer Stem Cells and Pediatric Solid Tumors
Recently, a subpopulation of cells, termed tumor-initiating cells or tumor stem cells (TSC), has been identified in many different types of solid tumors. These TSC, which are typically more resistant to chemotherapy and radiation compared to other tumor cells, have properties similar to normal stem cells including multipotency and the ability to self-renew, proliferate, and maintain the neoplas...
متن کاملNatural killer cells and solid tumors.
Natural killer (NK) cells play an important role in the innate immune response against cancer, in particular in the elimination of tumor metastases and small tumors. NK cell-mediated control of large solid tumors is usually not efficient, although tumors often express high amounts of activating ligands and low levels of inhibitory ligands, such as MHC class I. Thus, we assume that these tumors ...
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ژورنال
عنوان ژورنال: Cancer
سال: 1971
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197102)27:2<455::aid-cncr2820270233>3.0.co;2-5